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Cerebral Microbleeds Pathophysiology to Clinical Practice


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Cerebral Microbleeds Pathophysiology to Clinical Practice
Cerebrovascular diseases (including symptomatic strokes and vascular cognitive impairment) are arguably the leading cause of death and disability worldwide. About one in three symptomatic strokes are caused by diseases of small perforating arteries,
including most cases of spontaneous intracerebral hemorrhage, the most severe and lethal type of stroke. Despite the clear importance of small vessel diseases, many effective interventions (for example endovascular techniques) currently target only disease of large arteries, because small vessels are technically inaccessible and the underlying mechanisms of small vessel diseases remain relatively poorly understood.

The Ischemic Penumbra


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The Ischemic Penumbra
In the world of acute ischemic stroke, nothing is more important than an understanding of the ischemic penumbra. The whole concept of the existence of salvageable tissue, that is, the penumbra, is based on the daily clinical observation of almost immediate and early recovery from an episode of hemiparesis or other clinical expression of occlusion of a blood vessel within any of the arterial territories of the brain. Indeed, even before there was an appreciation of the complexities of the ischemic cascade, many clinicians dealing with stroke understood that something akin to the ischemic penumbra was likely to exist. These ideas, which fueled pivotal experimental studies to document the penumbra, clashed with the then prevailing dogma that the ischemic brain was doomed to die within minutes of onset of the clinical event. It is because of this central positioning of the penumbra in stroke outcome and therapy that we felt that a volume dedicated to its existence was timely.

Guía de práctica clínica sobre el manejo del traumatismo craneoencefálico en el ámbito extra e intrahospitalario de la CAPV


Datos del Libro

Guía de práctica clínica sobre el manejo del traumatismo craneoencefálico en el ámbito extra e intrahospitalario de la CAPV. Español | PDF | Autores: Garibi J, Aginaga JR, Arrese-Igor | Editorial Osakidetza | 1 Edición | 2007 | 152 Páginas | 1 Mb
Descripcion del Libro “Guía de práctica clínica sobre el manejo del traumatismo craneoencefálico en el ámbito extra e intrahospitalario de la CAPV“
Esta nueva Guía de Práctica Clínica (GPC) que publica Osakidetza, se enmarca en un importante proyecto de realización de GPC cuyo objetivo es servir de ayuda a los profesionales en la toma de decisiones en el ámbito de su trabajo diario.