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Category Archives: Vasculitis

“TISSUE ENGINEERING OF THE AORTIC HEART VALVE FUNDAMENTALS AND DEVELOPMENTS”


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“TISSUE ENGINEERING OF THE AORTIC HEART VALVE FUNDAMENTALS AND DEVELOPMENTS”
In the last 40 years, the study of aortic heart valve replacements has had its roots in the
work of great clinicians, scientists and biomedical engineers who established the techniques for heart valve substitutes. Recently, the research on the development of aortic heart valve replacements has shifted toward tissue engineering (TE), a multidisciplinary research that involves biological, biomaterial and bioengineering sciences. This book introduces current valve substitutes and their limitations and the futuristic tissue engineering of aortic heart valves (TEHV).

“Biology of Vascular Smooth Muscle Vasoconstriction and Dilatation”


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“Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation”
The discovery that the vascular contractility is regulated by a potent diffusible factor derived from the endothelium made by Furchgott and Zawadzki in 1980 is an epoch-making milestone in vascular biology. For a long time, the endothelium has been largely considered as a selective permeable barrier between the circulating blood and the vascular smooth muscle. Intensive studies evoked by Furchgott and Zawadzki’s work since then have firmly established that the endothelium-derived nitric oxide, prostanoids, endothelin, and endothelium-dependent hyperpolarization play a dominant role in the regulation of vascular activities both under physiolog- ical and pathophysiological conditions.

Vasculitis – Olga Vera Lastra , José Halabe Cherem


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Vasculitis – Olga Vera Lastra , José Halabe Cherem
Hace poco más de 35 años confronté mi primera experiencia con el concepto de vasculitis. Reconozco y acepto mi más completa y absoluta ignorancia de lo que este término significaba. De ahí surgió mi fascinación por lo que ahora podemos ser capaces de reconocer, identificar, diferenciar y tratar cuando estas manifestaciones clínicas ocurren en un importante grupo de pacientes que seguimos incluyendo como un conjunto de padecimientos cuyo denominador común es el daño vascular.

El concepto inicial de Kussmaul y Maier (1866) de relacionar la infestación por triquina con la poliarteritis nodosa quedó en el olvido por los mismos autores cuando,