Clinical Allergy Diagnosis and Management – G. Volcheck | Rincón Médico

Clinical Allergy Diagnosis and Management – G. Volcheck


Datos del Libro
Clinical Allergy – Diagnosis and Management – G. Volcheck
Contents
1 Overview of the Human Immune Response
1.1 Introduction .
1.2 Innate Immune System
1.3 Acquired Immune System
1.3.1 Immunogens and Allergens
1.3.2 Antigen-Presenting Cells

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1.3.3 Major Histocompatibility Complex
1.4 T- and B-Cells in the Acquired Immune Response
1.4.1 T-Lymphocytes
1.4.2 B-Lymphocytes and Immunoglobulins
1.5 Lymphoid Tissues
1.6 Tolerance: Distinguishing Self from Nonself
1.7 Cytokines
1.7.1 Cytokines Produced by Antigen-Presenting Cells
1.7.2 Cytokines in the Humoral Immune Response
1.7.3 Cytokines in the Cellular and Cytotoxic
Immune Response
1.7.4 Cytokines in the Allergic Immune Response
1.7.5 Anti-Inflammatory Cytokines
1.8 Chemokines
1.9 Complement
1.10 Inflammatory Cells
1.10.1 Eosinophils
1.10.2 Mast Cells
1.10.3 Basophils
1.11 Primary Mediators of Inflammation
1.11.1 Histamine
1.11.2 Arachidonic Acid Metabolism
1.11.3 Cyclooxygenase Products: Prostaglandins
1.11.4 Lipooxygenase Products: Leukotrienes
1.12 Allergic Response to an Allergen: Summary
1.13 Immune-Modulating Medications in Allergic Disease
1.13.1 CpG-DNA
1.13.2 Omalizumab
1.13.3 Anti-TNF
1.13.4 Immunotherapy
1.13.5 Corticosteroids
1.13.6 Immunophilins
1.14 Summary
Suggested Reading
2 Environmental Allergens
2.1 Overview of Allergens
2.2 Pollens
2.2.1 Pollen Counts
2.2.2 Tree Pollens
2.2.3 Grass Pollens
2.2.4 Weed Pollens
2.2.5 Environmental Control: Outdoor Pollens
2.3 Fungal Allergens
2.3.1 Classification
2.3.2 Alternaria alternata
2.3.3 Aspergillus
2.3.4 Cladosporium herbarum
2.3.5 Penicillium
2.3.6 Basidiomycetes
2.3.7 Other Fungi
2.3.8 Avoidance of Fungal Allergens
2.4 Indoor Allergens
2.4.1 Mite Allergens
2.4.2 Mite Allergen Avoidance
2.5 Animal Allergens
2.5.1 Cat Allergen
2.5.2 Dog Allergen
2.5.3 Horse Allergen
2.5.4 Cow Allergen
2.5.5 Mouse Allergen
2.5.6 Rat Allergen
2.5.7 Guinea Pig Allergen
2.5.8 Rabbit Allergen
2.5.9 Animal Allergen Environmental Control
2.6 Cockroach Allergen
2.6.1 Cockroach Environmental Control
2.7 Clinical Vignettes
2.7.1 Vignette 1
2.7.2 Vignette 2
2.7.3 Vignette 3
Suggested Reading
3 Allergen Testing and Allergen Immunotherapy
3.1 Allergen Testing
3.1.1 Skin Prick Testing
3.1.2 Skin Intradermal Testing
3.1.3 In Vitro Testing
3.2 Allergen Immunotherapy
3.2.1 Clinical Effectiveness of Allergen Immunotherapy
3.2.2 Immunologic Changes in Immunotherapy
3.2.3 Practical Considerations in Allergen Immunotherapy
3.2.4 Duration of Immunotherapy
3.2.5 Safety of Allergen Immunotherapy
3.2.6 Allergen Immunotherapy in Children
3.2.7 Allergen Immunotherapy in Pregnancy
3.2.8 Future Allergen Immunotherapy
3.3 Summary
3.4 Clinical Vignettes
3.4.1 Vignette 1
3.4.2 Vignette 2
3.4.3 Vignette 3
3.4.4 Vignette 4
Suggested Reading
4 Allergic Rhinitis and Rhinosinusitis
4.1 Overview
4.2 Nasal Anatomy and Function
4.3 Clinical Overview
4.4 Allergic Rhinitis
4.4.1 Pathophysiology
4.4.2 History
4.4.3 Physical Examination
4.4.4 Testing
4.4.5 Treatment
4.5 Nonallergic Rhinitis and Rhinosinusitis
4.6 Infectious-Acute Rhinosinusitis
4.6.1 Physical Examination
4.6.2 Microbiology
4.6.3 Testing
4.6.4 Treatment
4.7 Chronic Rhinosinusitis
4.8 Infectious Chronic Rhinosinusitis
4.8.1 Testing
4.8.2 Treatment
4.9 Allergic Fungal Rhinosinusitis
4.10 Chronic Eosinophilic (Fungal or Hyperplastic) Rhinosinusitis
4.11 Systemic Disease
4.12 Noninfectious Structural Rhinosinusitis
4.12.1 Nasal and Sinus Polyposis
4.12.2 Tumors
4.12.3 Foreign Body
4.12.4 Adenoidal Hypertrophy
4.12.5 Cerebrospinal Fluid Rhinorrhea
4.12.6 Septal Deviation
4.13 Noninfectious Nonstructural Rhinitis and Rhinosinusitis
4.13.1 Vasomotor Rhinitis
4.13.2 Nonallergic Rhinitis with Eosinophilia Syndrome
4.13.3 Atrophic Rhinitis
4.13.4 Hormonal Rhinitis
4.13.5 Medication-Induced Rhinitis
4.13.6 Rhinitis from Food Ingestion
4.14 Clinical Vignettes
4.14.1 Vignette 1
4.14.2 Vignette 2
4.14.3 Vignette 3
4.14.4 Vignette 4
4.14.5 Vignette 5
Suggested Reading
5 Allergic Eye Disease
5.1 Overview
5.2 Basic Eye Anatomy
5.3 Approach to the Patient
5.4 Allergic and Allergic-Like Eye Disease
5.4.1 Seasonal Allergic Conjunctivitis
5.4.2 Perennial Allergic Conjunctivitis
5.4.3 Atopic Keratoconjunctivitis
5.4.4 Vernal Conjunctivitis
5.4.5 Giant Papillary Conjunctivitis
5.4.6 Infectious Conjunctivitis
5.4.7 Contact Dermatoconjunctivitis
5.4.8 Blepharoconjunctivitis
5.4.9 Dry Eye Syndrome
5.5 Clinical Vignettes
5.5.1 Vignette 1
5.5.2 Vignette 2
5.5.3 Vignette 3
5.5.4 Vignette 4
Suggested Reading
6 Asthma
6.1 Overview
6.2 Epidemiology
6.3 Pathophysiology
6.3.1 Genetics
6.3.2 Airway Obstruction
6.3.3 Airway Hyperresponsiveness
6.3.4 Fatal Asthma
6.4 Clinical Presentation and Differential Diagnosis
6.4.1 Differential Diagnosis in Children
6.4.2 Differential Diagnosis in Adults
6.4.3 Testing
6.5 Classification of Asthma
6.5.1 Types
6.5.2 Initial Evaluation of Chronic Asthma Severity
6.6 Evaluation of Factors Contributing to Asthma Severity
6.6.1 Allergens
6.6.2 Infections
6.6.3 Exercise
6.6.4 Vocal Cord Dysfunction
6.6.5 Irritants and Pollutants
6.6.6 Rhinosinusitis (United Airway Hypothesis)
6.6.7 Smoking
6.6.8 Medications
6.6.9 Occupational
6.6.10 Obstructive Sleep Apnea
6.6.11 Gastroesophageal Reflux Disease
6.7 Treatment
6.7.1 Patient Education
6.7.2 Pharmacologic Therapy
6.7.3 Treatment of an Acute Asthmatic Attack
6.7.4 Status Asthmaticus Treatment
6.7.5 General Approach…………………………………
That Mimic Anaphylaxis or Idiopathic
Anaphylaxis
11.9 Management
11.9.1 Acute Management
11.9.2 Further Management
11.10 Clinical Vignettes
11.10.1 Vignette 1
11.10.2 Vignette 2
11.10.3 Vignette 3
Suggested Reading
12 Stinging Insect Allergy
12.1 Introduction
12.2 Identification of Stinging Insects
12.3 Reactions to Stinging Insects
12.3.1 Large Local Reaction
12.3.2 Systemic Reaction
12.3.3 Toxic Reaction
12.3.4 Non-IgE Reactions
12.4 Diagnostic Testing
12.5 Management
12.5.1 Acute Management
12.5.2 Avoidance Measures
12.5.3 Venom Immunotherapy for Hymenoptera
12.6 Conclusion
12.7 Clinical Vignettes
12.7.1 Vignette 1
12.7.2 Vignette 2
12.7.3 Vignette 3
Suggested Reading
Index

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