“ Hypertension And Cardiovascular Disease ” reviews the recent advances in understanding the pathophysiology and the fundamental diagnostic, clinical, and therapeutic aspects of arterial hypertension.
It was with great pleasure that I proceeded in the fulfi llment of this venture for two reasons:
First , I felt that despite the considerable bulk of existing literature, the need for such a book is great as knowledge in the fi eld has progressed rapidly over the past years. New large randomized controlled trials and meta-analyses have been published recently providing evidence for a lower blood pressure target for many patients. The impact of these “landmark” studies on hypertension guidelines remains to be seen in the near future. As a hypertension specialist, my ultimate goal is to apply evidence-based medicine to each patient attending the Hypertension Center that I have run at Evangelismos General Hospital for almost two decades and which has been recognized as an Excellence Center by the European Society of Hypertension. Evidence-based practice is not a new concept. It is the integration of best research evidence with clinical expertise and patient values. Personally, I strongly urge my attending and resident physicians to use their clinical skills and past experience to rapidly identify each patient’s unique health state and diagnosis, individual risks and benefi ts of potential treatment strategies, taking into account their patient’s personal health status and expectations. Getting the most of each clinical encounter will guide them into making appropriate clinical decisions for their patients.
Second , my vision is to offer to young physicians and other scientists engaged in the clinical cardiovascular fi eld a book that integrates basic medical science knowledge with applied clinical medicine, keeping in mind that physician-scientists are a vital force in transforming clinical observations into testable research hypotheses and translating research fi ndings into medical advances, thus having a substantial effect on people’s lives. Therefore, the main goal of this book is to inspire young physicians and urge them to become a critical resource in the future for assuring excellence in medical education and to teach their students that the basis of medicine is science and that scientific rigor should apply to patient care as well as research.
1. Hypertension: A Growing Threat
2. Techniques for Measuring Blood Pressure in the Office Setting.
3. Home Blood Pressure Measurements
4. 24-hour Ambulatory Blood Pressure Measurements
5. Central Blood Pressure Measurement
6. The Progression of Hypertensive Heart Disease to Left Ventricular Hypertrophy and Heart Failure
7. Systemic Hemodynamics in Hypertension
8. Structural Alterations in the Hypertensive Heart Disease Result in Intercalated Disc Remodeling and Arrhythmias
9. Prevention and Treatment of Atrial Fibrillation in Patients with Hypertension
10. Echocardiographic Assessment of Hypertensive Patients
11. Biomarkers of Oxidative Stress in Human Hypertension
12. The Role of Diet in the Prevention of Cardiovascular Disease
13. The Role of Exercise and Physical Activity in the Prevention of Hypertensive Heart Disease
14. Hypertension and Atherosclerosis: Pathophysiology, Mechanisms and Benefits of BP Control
15. Selecting Optimum Antihypertensive Therapy
16. The J-Curve Phenomenon in Hypertension
17. Follow-Up of the Hypertensive Patients with Cardiovascular Disease
18. Hypertension and Sudden Cardiac Death
19. Approach to Erectile Dysfunction in Patients with Hypertension and Coronary Artery Disease
20. Postmenopausal Hypertension and Coronary Artery Disease Risk
21. “The Economic Burden of Hypertension”
22. Hypertension; Grey Zones, Future Perspectives
Title: Hypertension and Cardiovascular Disease
Author: Emmanuel A. Andreadis